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KMID : 0828520150190030176
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Journal of the Korean Geriatrics Society
2015 Volume.19 No. 3 p.176 ~ p.180
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Acute Pancreatitis Induced by Quetiapine in an Elderly Patient
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Lee Hak-Chul
Choi Jong-Kyoung
Koh Jung-A
Kim Seon-Jae
Chu Seong-Taek
Kim Si-Eun
Choi Seung-Kyu
Nam Seung-Woo
Kwon Hyeok-Choon
Jung Ju-Won
Jeong In-a
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Abstract
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Quetiapine is an atypical antipsychotic that is frequently used to manage delirium in geriatric patients. Acute pancreatitis associated with quetiapine has rarely been reported. A 70-year-old male presented with severe abdominal pain a few hours after taking a dose of quetiapine prescribed for delirium. Despite the lack of risk factors of pancreatitis in his medical history, the patient had a slight increase of serum lipase and amylase levels. His general condition improved on discontinuation of quetiapine. A month later, quetiapine was readministered for the recurrence of delirium. Subsequently, the patient developed the same symptom with a significant increase in serum pancreatic enzyme levels, confirming that quetiapine induced the pancreatitis. We reported the first case of quetiapine-induced pancreatitis in Korea, together with a review of the literature.
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KEYWORD
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Acute pancreatitis, Quetiapine, Delirium
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